CARSILA

Reference number: ME 10145

Start / End date: 2010 / 2012

 

List of Participating Institutions:

Technical University of Liberec, Faculty of Mechanical Engineering, Department of Material Science, Czech Republic

Charles University in Prague, 2nd Faculty of Medicine Charles University, Czech Republic

Technical University of Lodz, Faculty of Mechanical Engineering, Poland

 

Project abstract:

The CARSILA project is a common undertaking of POLAND and CZECH REPUBLIC concerning one aim where each partner conducts the biological and/or mechanical investigations of carbon and silver based coatings deposited onto metallic implants using the innovative RF PACVD/MS method (the polish part) and nanofibres modified by RF/MW plasma or doped by carbon powder particles (the czech part) in order to get a market product in a form of bacteriostatic medical implant supported by the biocompatible textile material making the healing process faster.

 

The main goal of the project is the initiation of better after-treatment and simplification of after-care of the patients with implanted medical devices. Modified germicidal surface of the medical implant together with dressing, sterile and medicinal at once, can significantly decrease a number of infections developing after implanting operations. It is also worth to notice that the Institute of Materials Science and Engineering at the Technical University of Lodz has a great experience in deposition of NCD (Nanocrystalline Diamond) coatings onto intramedullary interlocking nails available in the Medgal Company commercial offer (patent No (11) 199898).

 

According to the great variety of products available on the market which contain in their composition silver particles, together with growing number of publications devoted to silver doped DLC layers appearing in the world literature, such a combination of protective coating on the implant’s surface seems to be intentional and justified. Moreover from the technological point of view addition of silver particles into DLC matrix will not affect the perfect mechanical and tribological properties of diamond-like carbon layers which can be critical for many biomedical applications, such as the hip joint prosthesis implants.

 

Application of carbon nanoparticles and plasma treatment for the nanofibres properties modification constitutes an innovative solution in the field of application of textile materials into wound dressing industry. The Textile Division at the Technical University of Liberec is the leading unit in the production and functionalization of nanofibres especially for the medical applications. Biocompatible, antioxidant and anticancerogenic properties of carbon nanoparticles introduced into submicron polymer structure during the core-shell electrospinning process as well as the plasma modification of nanofibres surface may have a great potential in the biomedical applications especially to intensify the healing processes.

 

Despite of the fact that the subject of silver – carbon nanocomposite layers is actual and many research results can be found in this field, there is a lack of literature reports concerning the mechanical and biological properties of Ag doped carbon layers synthesized with use of the proposed technology – RF PACVD/MS method - simultaneous work of radio frequency (13,56 MHz) plasma and Magnetron Sputtering process into one reaction chamber. Also the core shell electrospinning and plasma modification processes results will fill up the gap in the state of the art in the submicron structures modifications.

 

The expected result of this project is the worked out technology, its verification and – as the next step – a biological check in order to introduce into the market the safe product pointing the bacteriostatic properties. We already have an interest declaration of this project results from the company, which is a polish market leader in the medical implants fabrication.